After the Lizard was defeated (for the first time), Connors and Ratha permanently quit their works, and Connors was locked in a mental institute.
Ratha's experiments with lizard DNA were an unsuccessful attempts to cure him, until Connors used the serum on himself, transforming into the monstrous Lizard as a result. It is also mentioned that the is the founder of Oscorp. Not very much is known about Norman, other than that he had a debilitating disease called 'Retroviral Hypodysplasia' which eventually killed him. Connors, thinking that there is too much risk, refuses to do so, and Ratha fires him as a result. Connors to develop an antidote that would cure Osborn of a rare but deadly disease. Osborn is never seen in person, however, but is mentioned several times. Curt Connors' development of the regenerative serum. It is mentioned that he has been afflicted by an illness, which is the catalyst for Dr. Humorously, his silhouette is shown holding an orange globe of the company's logo, a subtle reference to his goblin bombs. Early in the film, he is shown as a vague silhouette on a monitor in the Oscorp lobby, referencing him as the company's founder. In The Amazing Spider-Man, Norman Osborn's existence is revealed via intercharacter dialogue and the presence of Oscorp Industries. When his son, Harry, was young, he sent him into the boarding school, causing their relationship to falter. Barely anything is known about Norman Osborn's early life, except for that he founded the Osborn Corporation, which he and everyone else nicknamed Oscorp, and became wealthy out of the company's success.
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